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Pasteur International Center for Research on Emerging Infectious Diseases (PICREID) takes an inter-continental One Health approach designed to improve the capacity to respond rapidly and effectively to outbreaks. PICREID identifies factors influencing emergence and transmission at the virus, vector, and reservoir level leading to epidemics in suspected spillover conditions. The consortium concentrates on high priority RNA viruses with epidemic potential in Africa (Rift Valley Fever virus (RVFV), Crimean Congo Hemorrhagic Fever Virus (CCHFV)) and in Southeast Asia (dengue virus (DENV)), as well as viruses (Disease X) identified from symptomatic surveillance or vector sampling.

PICREID focuses on significant needs in their study of these pathogens, including: 1) harmonizing pathogen identification and diagnostic tools; 2) improving existing diagnostic tools with more rapid, efficient, and specific point-of-need tools for better response to an outbreak in remote areas, including unknown viruses; 3) refining understanding on the prevalence, transmission, and adaptation of pathogens in humans, animal reservoirs, and insect vectors in specific environments; and 4) improving knowledge of disease pathogenesis and immune responses in hosts leading to drug/vaccine development.

This Research Center was supported by the National Institute of Allergy and Infectious Diseases of the National Institutes of Health under Award Number U01AI151758